Assessment of human diploid genome assembly with 10x Linked-Reads data
نویسندگان
چکیده
منابع مشابه
ARCS: scaffolding genome drafts with linked reads
Motivation Sequencing of human genomes is now routine, and assembly of shotgun reads is increasingly feasible. However, assemblies often fail to inform about chromosome-scale structure due to a lack of linkage information over long stretches of DNA-a shortcoming that is being addressed by new sequencing protocols, such as the GemCode and Chromium linked reads from 10 × Genomics. Results Here,...
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ژورنال
عنوان ژورنال: GigaScience
سال: 2019
ISSN: 2047-217X
DOI: 10.1093/gigascience/giz141